Three variants. One food.

The Sardine Protocol is the same metabolic event run at three doses. The 3-Day Reset is the on-ramp. The 5-Day is the standing monthly baseline for engaged practitioners — the cycle the protocol is actually designed around. The 7-Day Extended is the advanced cycle, run once or twice a year by the small subset of the cohort that runs it at all.

Which variant fits you?

Two questions. Pick the answer that describes you and follow the link.

The three variants

Each protocol is a complete, citation-backed walkthrough — what it is, who it’s for, the mechanism in five minutes, the hour-by-hour, the refeed, and the common mistakes.

At a glance

3-Day5-Day7-Day
Duration3 days5 days7 days
CadenceOn-ramp / occasionalMonthly (standing baseline)Once or twice / year
Who it's forFirst-timers, gateway practitionersEngaged practitioners with prior 3-day cyclesAdvanced practitioners with prior clean 5-day cycles
Biomarker trackingOptionalRecommendedRequired
Physician oversightNot required (healthy adults)Recommended if any medical historyRequired for any medical complexity
Refeed length3 days5 days7 days (structured)
Public guidance coversEverything (no gating)Full overview; optimization gatedFull overview; advanced detail gated

Read this first.

Every variant has hard exclusion criteria — Type 1 diabetes, T2D on insulin or sulfonylureas, eating disorder history, pregnancy, BMI under 18.5, and several others. The Safety page has the complete list with the medical rationale for each. Read it before you start.

Get the cheat sheet

A free 4-page PDF with the protocol overview, brand shopping list, day-by-day at a glance, refeed quick rules, and the warning signs that tell you to stop.

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Looking for the brand-by-brand sardine comparison? The buying guide is here.